PerPlot & PerScan: tools for analysis of DNA curvature-related periodicity in genomic nucleotide sequences.

PerPlot & PerScan: tools for analysis of DNA curvature-related periodicity in genomic nucleotide sequences.

BACKGROUNDPeriodic spacing of brief adenine or thymine runs phased with DNA helical interval of ~10.5 bp is related to intrinsic DNA curvature and deformability, which play essential roles in DNA-protein interactions and in the group of chromosomes in each eukaryotes and prokaryotes. Local variations in DNA sequence periodicity have been linked to variations in gene …

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